Collection

GLP-1 compounds

Medicines and investigational drugs that activate the GLP-1 receptor, alone or together with the GIP or glucagon receptors.

4 compounds

Educational only. A summary of published research, not medical advice or a recommendation. No doses are listed.

GLP-1 compounds (4)

  • Semaglutide

    FDA-approved

    GLP-1 & weight-loss peptides · Large human trials

    A long-acting GLP-1 receptor agonist that lowers blood sugar, slows stomach emptying and reduces appetite.

  • Tirzepatide

    FDA-approved

    GLP-1 & weight-loss peptides · Large human trials

    A once-weekly dual agonist of the GIP and GLP-1 receptors used for type 2 diabetes and weight management.

  • Retatrutide

    Investigational

    GLP-1 & weight-loss peptides · Large human trials

    An investigational once-weekly “triple agonist” that acts on the GIP, GLP-1 and glucagon receptors.

  • Survodutide

    Investigational

    GLP-1 & weight-loss peptides · Early or small human studies

    An investigational dual agonist of the glucagon and GLP-1 receptors.

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