Compound profile
Epitalon
Also known as Epithalon
Last reviewed October 2026
Educational only. A summary of published research, not medical advice or a recommendation. No doses are listed.
Quick take
A synthetic four-amino-acid peptide modeled on epithalamin, an extract of the pineal gland.
- Class
- Other research peptides
- Status
- Not approved
- Evidence
- Mostly animal & lab studies
- Half-life
- Not well documented
Mechanism fingerprint
What it acts on, and how. Each chip links to that pathway on the map.
Studied for effects on telomerase, melatonin rhythm and aging, mostly in cells and animals.
What makes it different
Modeled on a pineal-gland extract and studied for telomerase and aging, mostly in cells and animals.
Compare side by side
Mechanism & pathways
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Studied link
Telomerase
cell studies
An enzyme that rebuilds telomeres, the protective caps on chromosomes that shorten each time a cell divides.
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Studied link
Melatonin rhythm
animal studies
Melatonin, made by the pineal gland at night, helps set the body's sleep–wake rhythm.
Evidence overview
Mostly animal & lab studies
Most research comes from one group in Russia and has not been confirmed in large independent human trials.
A breakdown into human, animal and cell studies hasn't been added for this compound yet.
Why it's used
Used in the hope of slowing aging, based on Russian research.
Side effects & risks
Reported side effects
- Not well characterized in humans
Risks and warnings
- Long-term safety unknown
- Products sold as “research use only” are not quality-controlled medicines; purity, sterility and labeled amount are not verified.
FAQ
Short answers taken from this profile.
What is Epitalon?
A synthetic four-amino-acid peptide modeled on epithalamin, an extract of the pineal gland.
How does Epitalon work?
Studied for effects on telomerase, melatonin rhythm and aging, mostly in cells and animals.
What receptors or pathways does Epitalon act on?
telomerase (studied link; cell studies) and melatonin rhythm (studied link; animal studies). Links marked “studied” or “proposed” come from early research and aren't confirmed in people.
How is Epitalon different from similar compounds?
Modeled on a pineal-gland extract and studied for telomerase and aging, mostly in cells and animals.
Is Epitalon approved?
Not approved for human use.
What has Epitalon been studied for?
Used in the hope of slowing aging, based on Russian research.
How strong is the evidence?
Mostly animal & lab studies. Most research comes from one group in Russia and has not been confirmed in large independent human trials.
What are the main risks?
Long-term safety unknown. Products sold as “research use only” are not quality-controlled medicines; purity, sterility and labeled amount are not verified.