CoachP

Effect

GH / IGF-1

Raising the body's own growth hormone, and with it IGF-1, through the GHRH or ghrelin receptor in the pituitary gland.

4 compounds in the guide

Educational only. A summary of published research, not medical advice or a recommendation. No doses are listed. Compounds are listed from the strongest evidence to the weakest. Being listed isn't a recommendation.

Related pathways

The receptors and pathways behind this effect.

Compounds

  • Tesamorelin

    FDA-approved

    Growth hormone secretagogues · Large human trials

    A synthetic analogue of growth hormone–releasing hormone (GHRH) that prompts the pituitary to release growth hormone.

  • Sermorelin

    Previously approved

    Growth hormone secretagogues · Early or small human studies

    A shortened form of growth hormone–releasing hormone made of its first 29 amino acids.

  • CJC-1295

    Not approved

    Growth hormone secretagogues · Early or small human studies

    A synthetic GHRH analogue designed to last much longer than the body's own GHRH.

  • Ipamorelin

    Not approved

    Growth hormone secretagogues · Early or small human studies

    A synthetic five-amino-acid growth hormone secretagogue.

Other effects